Cinnamon: The Prevention of Insulin Resistance in Type 2 Diabetes
Cinnamon (Cinnamomum verum, C. zeylanicum) and cassia (C. aromaticum) have a long history of uses as spices, flavoring agents, preservatives, and pharmacological agents. Cinnamon Increases Insulin Sensitivity and Glucose Transport Insulin resistance is a core defect in obesity, type 2 diabetes mellitus (T2DM), and metabolic syndrome. Many data tell that Cinnamon Extract (CE) prevents the development of insulin resistance, by enhancing insulin signaling and possibly via the NO pathway in skeletal muscle. An aqueous extract of cinnamon has also been shown to improve insulin sensitivity in humans. Previous studies reported that CE increases glucose uptake and the glucose transporter (GLUT4) expression in adipose cells. It has been observed that a water extract of cinnamon reduced blood glucose, plasma insulin. Cinnamon Decreases Inflammation Tristetraprolin is an anti-inflammatory protein and a potential therapeutic target for the treatment of inflammation related diseases....